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The global bone grafts and substitutes market size is estimated to grow by USD 1.72 billion at a CAGR of 9.45% between 2023 and 2028. Primary factors that are driving the market growth include the growing prevalence of orthopedic conditions, the increasing demand for dental bone grafts, and the rising investment in clinical trials. Market expansion is notably propelled by the increasing prevalence of orthopedic conditions. As per the Arthritis Foundation, it's projected that by 2050, approximately 130 million individuals worldwide will suffer from degenerative joint diseases like osteoarthritis. These conditions necessitate treatments such as addressing fractures and dislocations in the lower extremities, performing total and partial hip replacements, and conducting spinal fusions. Utilized post-cervical or lumbar spine surgeries, growth stimulation devices administer low-intensity electrical signals to stimulate the innate healing process, particularly for spinal fusion procedures.
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The market share growth by the xenografts segment will be significant during the forecast period. Xenografts are defined as transplants between closely related species. They serve as biological dressings that protect wounds from bacterial and physical trauma. The growth of this segment is attributed to factors such as the increasing prevalence of knee and hip injuries, technological advances such as 3D-printed implants, and new product launches by key players.
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The xenografts segment was valued at USD 1.31 billion in 2018. Xenografts are widely used for R&D, as they create microenvironments closer to a tumor's physiological and pathological conditions. Therefore, the growth of the xenograft segment is expected to drive the global bone graft and substitute market during the forecast period.
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North America is estimated to contribute 41% to the growth of the global market during the forecast period. Technavio’s analysts have elaborately explained the regional trends and drivers will shape the market during the forecast period.
The growth of the market in the region is attributed to factors such as the rising prevalence of orthopedic conditions, product launches, favorable reimbursement for orthopedic implants, and awareness initiatives by governments and non-profit organizations. The increase in the prevalence of orthopedic conditions will augment the demand in the region. For instance, according to the CDC, the prevalence of arthritis in the US is expected to increase in the coming years. Vendors are promoting the use by providing performance guarantees. For instance, in February 2022, Orthofix Medical announced the launch of Opus BA, a synthetic bioactive bone graft solution. Therefore, the launch of new products and approvals for the inclusion of new indications are expected to drive market growth during the forecast period.
Companies are implementing various strategies, such as strategic alliances, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the market. The report also includes detailed analyses of the competitive landscape of the market and information about 20 market companies, including:
AlloSource, Arthrex Inc., Baxter International Inc., Bioventus LLC, Ed. Geistlich Sohne AG, Institut Straumann AG, Integra Lifesciences Corp., Johnson and Johnson Services Inc., Medtronic Plc, MTF Biologics, NovaBone Products LLC, Nuvasive Inc., Orthofix Medical Inc., OST Laboratories, RTI Surgical Inc., Smith and Nephew plc, Stryker Corp., TBF TISSUE ENGINEERING, Xtant Medical Holdings Inc., and Zimmer Biomet Holdings Inc.
AlloSource - The company offers solutions for bone grafts and substitutes, which comprise demineralized bone matrix in a reverse phase medium.
Qualitative and quantitative analysis of companies has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key market players. Data is qualitatively analyzed to categorize companies as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize companies as dominant, leading, strong, tentative, and weak.
The Market is experiencing notable growth, driven by the increasing prevalence of conditions such as degenerative disc disease (DDD), fractured bones, and facial fractures due to sports injuries, falls, and road accidents. With a growing geriatric population and rising demand for minimally invasive surgeries, the market for bone grafts and substitutes is witnessing significant traction. These products play a crucial role in orthopedic procedures such as joint reconstruction, spinal fusion, and dental bone grafts, addressing a wide range of conditions, including hip fractures, spinal injuries, and bone cancer. Synthetic substitutes, including powders, granules, pastes, and putties, offer viable alternatives to traditional bone tissue grafts, meeting the regulatory standards set by authorities and providing surgeons with versatile options for patient care. Our researchers analyzed the data with 2022 as the base year, along with the key drivers, trends, and challenges. A holistic analysis of drivers will help companies refine their marketing strategies to gain a competitive advantage.
The growing prevalence of orthopedic conditions is notably driving market growth. According to the Arthritis Foundation, by 2050, 130 million people across the world will have degenerative joint diseases or disorders such as osteoarthritis. They are used for treating conditions such as fractures and dislocation of the lower extremities, total and partial hip replacements, and spinal fusions. A growth stimulation device is used for spinal fusion after cervical or lumbar spine surgery to deliver low-intensity electrical signals, which stimulate the natural healing process. Various companies offer growth stimulation devices. For instance, Orthofix Medical Inc. has developed Physio-Stim for hip fractures. Therefore, the increasing prevalence of injuries and the availability of a wide variety of products are expected to drive the market during the forecast period.
The growing adoption of minimally invasive surgeries is a key trend influencing the market growth. Minimally invasive surgeries provide various benefits to patients, such as less pain and discomfort, low chances of infection and bleeding, shorter hospital stays, reduced chances of scars, and quick recovery. Minimally invasive surgeries are used for various procedures, such as arthroscopy, joint replacement, and spine fusion. The grafting technique is a new, minimally invasive technique that leads to improved outcomes with less pain and fewer complications. The presence of specialist orthopedic care centers is expected to increase the adoption of minimally invasive surgeries. Thus, the growing adoption of minimally invasive surgeries is expected to increase their use, which will fuel the market growth during the forecast period.
The high costs associated with implants and procedures may impede bone grafts and substitute market growth. Orthopedic implants are used for the treatment of conditions related to the joints, spine, and maxillofacial injuries. The cost depends on their applications and features. For instance, the cost of a simple graft is higher than the cost of synthetic substitutes. The high costs can increase the cost burden on end-users and patients. For instance, the average cost of inpatient bone grafting procedures ranges from USD 25,000 to USD 30,000. Post-surgical diagnostic tests can further increase the cost burden. For instance, the average cost of a CT scan ranges between USD 750 and USD 1,300 per orthopedic procedure. Such factors are expected to hinder the growth of the market during the forecast period.
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The market report includes the adoption lifecycle of the market, covering from the innovator’s stage to the laggard’s stage. It focuses on adoption rates in different regions based on penetration. Furthermore, the report also includes key purchase criteria and drivers of price sensitivity to help companies evaluate and develop their growth strategies.
Customer Landscape
The market research report provides comprehensive data (region wise segment analysis), with forecasts and estimates in "USD Billion" for the period 2024-2028, as well as historical data from 2018 - 2022 for the following segments.
The Market is experiencing rapid growth fueled by rising cases of bone disorders, fractures, and degeneration, necessitating effective treatment options. With advancements in medical technology, orthopedic procedures like joint replacements, spine surgeries, and fracture repairs are becoming increasingly common, driving the demand for bone grafts and substitutes. Players in the market are innovating with biocomposites, synthetic substitutes, and cell-based matrices to facilitate bone regeneration and repair. Surgeons utilize a variety of materials, including ceramics, polymers, and sterile calcium phosphate resorbable fillers, to address diverse orthopedic needs. The market is also witnessing increased adoption of minimally invasive procedures and long bone graft substitutes, catering to the growing geriatric population and addressing orthopedic disorders prevalent in medical tourism destinations. Regulatory authorities play a crucial role in ensuring the safety and efficacy of these products amidst growing healthcare infrastructure and demand.
Moreover, the market is experiencing significant growth within the healthcare sector, driven by factors such as bone fractures, degeneration, and diseases like osteoporosis and bone cancer. Surgeons frequently utilize bone grafts and substitutes in procedures ranging from joint replacements to craniomaxillofacial surgeries, addressing conditions such as spinal deformities and facial fractures. Technologies like HCCP and products like Osteo-P Synthetic Bone Graft Substitute offer innovative solutions for bone repair and regeneration. The market also benefits from the rising demand for medical tourism and the increasing incidence of road accidents and sports injuries necessitating fracture repair and spinal fusion surgeries. Regulatory frameworks ensure the safety and efficacy of bone graft materials, supporting the market's expansion in catering to diverse orthopedic needs.
Additionally, the market is witnessing substantial growth amidst increasing concerns related to bone degeneration, fractures, and spinal disorders. Allografts, bone morphogenic proteins (BMP), and sterile calcium phosphate resorbable bone void fillers are among the key substitutes utilized in orthopedic and craniomaxillofacial surgeries. Surgeons often rely on ceramic composites and HCCP technology to address degenerative disc disease (DDD) and joint replacement procedures, including knee and lumbar spinal fusion surgeries. The market is also buoyed by advancements in dental implant surgical procedures and foot & ankle surgeries, catering to the growing demand from the healthcare sector and medical tourism industry. Regulatory frameworks play a crucial role in ensuring the safety and efficacy of bone grafts and substitutes as organizations like Graftys and Renovos continue to innovate to meet the evolving needs of patients and surgeons alike.
Bone Grafts And Substitutes Market Scope |
|
Report Coverage |
Details |
Page number |
183 |
Base year |
2023 |
Historic period |
2018 - 2022 |
Forecast period |
2024-2028 |
Growth momentum & CAGR |
Accelerate at a CAGR of 9.45% |
Market growth 2024-2028 |
USD 1.72 billion |
Market structure |
Fragmented |
YoY growth 2023-2024(%) |
8.42 |
Regional analysis |
North America, Europe, Asia, and Rest of World (ROW) |
Performing market contribution |
North America at 41% |
Key countries |
US, Germany, UK, China, and Japan |
Competitive landscape |
Leading Vendors, Market Positioning of Vendors, Competitive Strategies, and Industry Risks |
Key companies profiled |
AlloSource, Arthrex Inc., Baxter International Inc., Bioventus LLC, Ed. Geistlich Sohne AG, Institut Straumann AG, Integra Lifesciences Corp., Johnson and Johnson Services Inc., Medtronic Plc, MTF Biologics, NovaBone Products LLC, Nuvasive Inc., Orthofix Medical Inc., OST Laboratories, RTI Surgical Inc., Smith and Nephew plc, Stryker Corp., TBF TISSUE ENGINEERING, Xtant Medical Holdings Inc., and Zimmer Biomet Holdings Inc. |
Market dynamics |
Parent market analysis, Market forecasting, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID-19 impact and recovery analysis and future consumer dynamics, Market condition analysis for market forecast period. |
Customization purview |
If our report has not included the data that you are looking for, you can reach out to our analysts and get segments customized. |
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1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Historic Market Size
5 Five Forces Analysis
6 Market Segmentation by Product
7 Market Segmentation by Application
8 Customer Landscape
9 Geographic Landscape
10 Drivers, Challenges, and Opportunity/Restraints
11 Competitive Landscape
12 Competitive Analysis
13 Appendix
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