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Extensive research carried out by the analysts at Technavio has shown that the global hypercholesterolemia drugs market is expected to reach more than USD 13 billion by 2020. Elevated levels of cholesterol in the blood lead to its deposition in the arterial walls, eventually leading to atherosclerosis. This results in the narrowing of blood vessels, decreasing blood flow to the heart muscles that might induce a heart attack.
High cholesterol levels constitute for nearly one-third of the ischemic heart disease and stroke in developing nations like India and China. According to WHO, in men aged above 40 years, a 10% decrease in serum cholesterol level reduces the risk of heart disease by almost 50% within five years. Therefore, as per the cardiovascular risk management guidelines, it is imperative to reduce the blood cholesterol level to significantly lower the risk of cardiovascular diseases.
In the market research study, the analysts have estimated factors the increasing use of combination therapies to contribute to the growth of this market in the coming years. Combination drugs are mostly used for managing lipid abnormalities. Combination drugs have advantages over monotherapies both in terms of efficacy and reduced incidences of adverse effects. Also, combination drugs are priced lower, have simpler logistics distribution, and show improved patient compliance than monotherapy.
During 2015, statins dominated the market and accounted for more than 80% of the market share in terms of revenue. Statins are structural analogs of the HMG-CoA enzyme and block HMG-CoA reductase enzyme activity, which catalyzes the rate-limiting step in de novo cholesterol synthesis. By lowering the blood cholesterol levels, statins bring down the danger of chest pain, heart attack, and stroke caused by a blocked blood vessel.
The Americas dominated the global hypercholesterolemia drugs market and accounted for more than 56% of the market share in terms of revenue. This market is expected to witness declining growth, owing to competition from the generic versions of branded drugs. For instance, Crestor by AstraZeneca is set to expire in the US in 2016 while Lipitor's patent expired in 2011. However, the market is expected to recover due to an increase in the patient pool.
The global hypercholesterolemia drugs market is highly competitive due to the presence of well-established global and regional providers. New players are also entering the market as they have huge growth opportunities. Also, large vendors are engaged in strategic alliances to market and manufacture drugs.
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PART 01: Executive summary
PART 02: Scope of the report
PART 03: Market research methodology
PART 04: Introduction
PART 05: Hypercholesterolemia: An overview
PART 06: Pipeline portfolio
PART 07: Market landscape
PART 08: Segmentation by type of disease
PART 09: Market segmentation by MOA
PART 10: Market segmentation by drug class
PART 11: Geographical segmentation
PART 12: Market drivers
PART 13: Impact of drivers
PART 14: Market challenges
PART 15: Impact of drivers and challenges
PART 16: Market trends
PART 17: Vendor landscape
PART 18: Key vendor analysis
PART 19: Appendix
PART 20: Explore Technavio
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