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The Freeze Drying Equipment Market size is estimated to grow by USD 3.88 billion at a CAGR of 10.26% between 2023 and 2028. The market's growth hinges on several factors, including advancements in freeze-drying technology, the superiority of freeze-drying compared to traditional drying methods, and the increasing demand for biobanks. These factors collectively contribute to the market's expansion, highlighting the growing significance of freeze-drying in various industries. Technological innovations in freeze-drying have led to improved efficiency and quality of dried products, driving their adoption across different sectors. Moreover, the benefits offered by freeze-drying, such as better preservation of product quality and longer shelf life, have fueled its demand among consumers. Additionally, the rising need for biobanks, which require effective preservation methods, has further bolstered the market for freeze-drying equipment and services.
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The market share growth by the tray style segment will be significant during the forecast period. Tray-style freeze dryers usually have a large rectangular reservoir with shelves, and products can be placed in trays, vials, and other containers on these shelves. They are used to freeze-dry a variety of materials, such as pharmaceutical solutions, tissue extracts, and vaccines, for long-term storage.
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The tray-style segment was valued at USD 2.50 billion in 2018. Tray-style freeze dryers are generally larger and more sophisticated than manifold freeze dryers. The major advantage of tray-style freeze dryers is that they allow products to be frozen in place and perform both primary and secondary freeze-drying, thus producing the driest possible end-products. They can also perform the freeze-drying of products in bulk or in vials/containers. During the freeze-drying of vials, the freeze-dryer is supplied with a stoppering mechanism that enables a stopper to be pressed into place in the dryer. It ensures the sealing of the vial before it is exposed to the atmosphere. Hence, tray-style freeze dryers are increasingly being used for the long-term storage of vaccines. Owing to such factors, this segment of the market is expected to grow during the forecast period.
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Europe is estimated to contribute 43% to the growth of the global market during the forecast period. Technavio’s analysts have elaborately explained the regional trends and drivers that shape the market during the forecast period.
The UK and Germany are the main revenue contributors to the market in Europe. The extensive focus of various pharmaceutical companies, such as Novartis and Sanofi, on developing novel drugs and vaccines and the increasing number of cancer biomarker studies are the main factors that drive the demand for this equipment in the region, as freeze-drying allows high storage stability for the labile biomolecules in drugs and vaccines.
Moreover, the high pharmaceutical spending across the region has also resulted in high drug consumption, which is positively impacting the demand for lyophilization. For instance, as per the OECD, Switzerland, Belgium, and Germany were the leading countries in Europe in terms of per capita pharmaceutical spending in 2020. Thus, the rising number of biopharmaceutical clinical trials and the growth in pharmaceutical spending are propelling the demand for freeze-drying equipment in Europe during the forecast period.
Our analysis of the adoption life cycle of the market indicates its movement between the innovator’s stage and the laggard’s stage. The report illustrates the lifecycle of the market, focusing on the adoption rates of the major countries. Technavio has included key purchase criteria, adoption rates, adoption lifecycles, and drivers of price sensitivity to help companies evaluate and develop growth strategies from 2023 to 2028.
Global Market Customer Landscape
The market is driven by the demand for food preservation and the need for contract manufacturing and lyophilization services. These services cater to the production of lyophilized products such as biologic drugs, injectable formulations, and diagnostic kits. The technology is also used in electron microscopy and biochemistry. With the expansion of food & beverage production facilities, the freeze-drying method has become crucial. Changing lifestyles, busy schedules, and inflating disposable incomes have increased the demand for freeze-dried products. Packaged food products can contribute to the spread of diseases. Additionally, freeze-drying equipment is essential for applications in military camps and spacecraft where preservation and storage are critical. Our researchers studied the data for years, with 2023 as the base year and 2024 as the estimated year, and presented the key drivers, trends, and challenges for the market.
The market growth is being driven significantly by the benefits of freeze-drying over conventional drying. This technology has been utilized for more than three decades to stabilize various chemical components and is gaining increasing usage in the pharmaceutical and biotechnology industries due to its potential advantages over conventional drying methods such as crystallization, filtration, and precipitation. The primary benefit of freeze-drying over conventional drying is the preservation of the chemical and biological potency and homogeneity of the final products. Furthermore, freeze-drying allows for easy dispensing and metering before final packaging, as well as protection against solution effects and chemical degradation. Compared to dry powder fills, freeze-drying can also increase the speed of rehydration.
Additionally, freeze-dried products can remain in their original state for years in appropriate packaging and storage conditions due to their low moisture content. In contrast, conventionally dried products have a higher moisture content than freeze-dried products, which makes them a breeding ground for mold and organisms. Consequently, conventionally dried products have a shorter shelf life than freeze-dried products. Moreover, freeze-drying allows samples to dry in their original containers, reducing the risk of altering their initial state. Thus, these benefits are likely to fuel the growth of the market during the forecast period.
The market is witnessing an emerging trend of smart freeze dryers. Companies are investing in research and development to achieve cost synergies and optimize processes to increase efficiency, lower operating costs, and reduce emissions. As remote monitoring technologies become more widely adopted for optimized results, the freeze-drying industry is following suit.
Moreover, companies in the market have introduced smart freeze dryers, which offer increased reliability and affordability. These dryers are based on standardized modules and are designed to meet the specific size and technology requirements of each customer. In addition to being cost-effective, these dryers also facilitate planning, validation, and documentation, significantly reducing delivery times. These factors are expected to drive the adoption of smart freeze dryers, thereby driving the market growth during the forecast period.
The market growth is being impeded by the emergence of potential alternatives to freeze-drying. Various methods such as spray drying, spray freeze-drying, atmospheric spray freeze-drying, and vacuum foam drying have emerged as potential alternatives to freeze-drying for producing dry formations of biopharmaceuticals. Among these, spray freeze-drying has gained popularity in recent years and has emerged as the most mature alternative to lyophilization. In spray freeze-drying, the sublimation and secondary drying of frozen particles are faster than those in conventional freeze-drying due to the increased surface area of the frozen starting material.
Additionally, it allows for the engineering of particle size and shape, enabling delivery methods that are infeasible with other drying techniques. Furthermore, it can process materials under atmospheric pressure and offers energy savings. Vacuum foam drying has also emerged as a potential approach in recent years for preserving sensitive biological materials. It is a short, simple, and industrially economical process for preserving biologics, which can offer better processing and storage stability to products such as bovine serum albumin compared to freeze-drying. Hence, the growing popularity of such alternatives is expected to constrain the growth of the global market during the forecast period.
Companies are implementing various strategies, such as strategic alliances, partnerships, mergers and acquisitions, geographical expansion, and product/service launches, to enhance their presence in the market.
Biopharma Process Systems Ltd. - The company offers biopharma equipment, cryopreservation equipment, contract research and manufacturing, and airflow equipment. The key offerings of the company include freeze-drying equipment.
Gevasol- The company offers Gevasol fluid control, Gevasol motion control, and Gevasol vacuum systems.
We also have detailed analyses of the market’s competitive landscape and offer information on 20 market companies, including:
Technavio report provides an in-depth analysis of the market and its players through combined qualitative and quantitative data. The analysis classifies companies into categories based on their business approaches, including pure-play, category-focused, industry-focused, and diversified. companies are specially categorized into dominant, leading, strong, tentative, and weak, based on their quantitative data analysis. Technavio report provides an in-depth analysis of the market and its players through combined qualitative and quantitative data. The analysis classifies companies into categories based on their business approaches, including pure-play, category-focused, industry-focused, and diversified. companies are specially categorized into dominant, leading, strong, tentative, and weak, based on their quantitative data analysis.
The market research report provides comprehensive data (region wise segment analysis), with forecasts and estimates in "USD Billion" for the period 2024 to 2028, as well as historical data from 2018 to 2022 for the following segments.
1. Lyophilization Equipment and Services Market Analysis North America, Europe, Asia, Rest of World (ROW) - US, Germany, UK, France, Japan - Size and Forecast
2. Industrial Dryers For Agricultural Products Market Analysis APAC, North America, Europe, South America, Middle East and Africa - US, China, UK, Germany, Japan - Size and Forecast
3. Freeze Dried Foods Market Analysis North America, Europe, APAC, South America, Middle East and Africa - US, China, Germany, UK, Canada - Size and Forecast
.The biotechnology industry plays a pivotal role in advancing healthcare and biopharmaceutical medications, benefiting astronauts, military personnel, and the broader population. Techniques like vacuum microwave dehydration and atmospheric freeze drying are integral in maintaining the efficacy of biological components such as proteins and enzymes. Lyophilization, or freeze drying, is critical in pharmaceutical and biotechnology manufacturing for preserving medications and biologics. Various scales of equipment, from bench top freeze dryers to industrial freeze dryers, cater to different needs across food processing and clinical research sectors. Clean in place systems and controlling and monitoring systems ensure the quality and safety of products during loading and unloading in drying chambers. The biologics market and biosimilars benefit from innovations in lyophilization contract manufacturing services, supporting medical applications and biorefineries. This technology also aids food processing facilities and dairy industries in preserving nutritional quality and extending shelf life, crucial for catering to the geriatric population and managing chronic diseases effectively.
Moreover, glycerol is a key component in atmospheric freeze drying, a process crucial for controlling moisture levels in various products. Freeze drying methods include tray style freeze dryers, shell freeze dryers, and industrial scale lyophilization equipment for large-scale production, alongside pilot scale and laboratory scale lyophilization equipment for research and development. This technology is vital in the food processing and packaging industry, ensuring the preservation of food quality and shelf life. Loading and unloading systems and manifolds facilitate efficient handling during the freeze drying technique. Mobile freeze dryers and laboratory freeze dryers cater to different operational needs, while general purpose freeze dryers utilize high pressure vacuum to remove water vapor from substances like platelet rich plasma, viruses, and bacteria. Freeze drying also supports the production of penicillin, cell and gene therapies, and biologics and biosimilars in bio refineries and laboratory settings, ensuring product stability and efficacy.
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Market Scope |
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Report Coverage |
Details |
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Page number |
177 |
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Base year |
2023 |
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Historic period |
2018 - 2022 |
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Forecast period |
2024-2028 |
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Growth momentum & CAGR |
Accelerate at a CAGR of 10.26% |
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Market growth 2024-2028 |
USD 3.88 billion |
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Market structure |
Fragmented |
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YoY growth 2023-2024(%) |
9.06 |
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Regional analysis |
Europe, APAC, North America, South America, and Middle East and Africa |
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Performing market contribution |
Europe at 43% |
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Key countries |
US, China, UK, Germany, and Japan |
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Competitive landscape |
Leading Companies, Market Positioning of Companies, Competitive Strategies, and Industry Risks |
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Key companies profiled |
ATS Automation Tooling Systems Inc., Azbil Corp., Biopharma Process Systems Ltd., BUCHI Labortechnik AG, Cuddon Freeze Dry, Freeze Drying Systems Pvt. Ltd., GEA Group AG, Gem Machinery and Allied Industries, Gevasol, HOF Sonderanlagenbau GmbH, IMA Industria Macchine Automatiche Spa, Labconco Corp., Lyophilization Systems India Pvt Ltd., Martin Christ Gefriertrocknungsanlagen GmbH, MechaTech Systems Ltd., Millrock Technology Inc., OPTIMA packaging group GmbH, Scala Scientific BV, Shanghai Tofflon Science and Technology Co. Ltd, and ZIRBUS technology GmbH |
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Market dynamics |
Parent market analysis, Market forecasting growth inducers and obstacles, Fast-growing and slow-growing segment analysis, Market growth and Forecasting, COVID 19 impact and recovery analysis and future consumer dynamics, Market condition analysis for forecast period |
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Customization purview |
If our market report has not included the data that you are looking for, you can reach out to our analysts and get segments customized. |
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1 Executive Summary
2 Market Landscape
3 Market Sizing
4 Historic Market Size
5 Five Forces Analysis
6 Market Segmentation by Product
7 Market Segmentation by Application
8 Customer Landscape
9 Geographic Landscape
10 Drivers, Challenges, and Opportunity/Restraints
11 Competitive Landscape
12 Competitive Analysis
13 Appendix
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