Binders Excipients Market Size 2024-2028

The binders excipients market size is forecast to increase by USD 354.5 million, at a CAGR of 4.5% between 2023 and 2028. The global binders excipients market is witnessing significant growth, driven by several key factors. One of the primary growth drivers is the increasing demand for cellulose-based binders, which are widely used in the pharmaceutical industry due to their superior binding properties and safety profile. Another trend influencing market growth is the demand for new excipients to develop easily consumable drugs, particularly in the growing generics and biosimilars sectors. Additionally, the loss of patents and patent expiry of key drugs has led to an influx of generic drugs, increasing the demand for cost-effective excipients. However, challenges such as stringent regulatory requirements and the high cost of raw materials may hinder market growth. Overall, the binders excipients market is expected to continue its growth trajectory, driven by these factors and the ongoing research and development in the pharmaceutical industry. The market growth analysis report also includes an in-depth analysis of drivers, trends, and challenges. Our market research and growth report examines historic data from 2018-2022, besides analyzing the current market scenario.

What will be the Market Size During the Forecast Period?

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Market Dynamics

The market plays a crucial role in solid oral dose forms, such as capsules, by facilitating the binding of hydrophilic molecules. It manages intermolecular interactions using cellulose derivatives and ensures the uniformity of powder mixture compressibility. These excipients influence flow characteristics and the controlled release of active ingredients, thus impacting the therapeutic effect of medicinal drugs. Utilizing both natural and synthetic polymers, along with sugars and starches, they create cohesive oral medicines for patients in tablets/capsules. The market thrives on dry form applications and wet form applications, driven by meticulous research methodology and subject-related expert advice.  Our research analysts have studied the historical data and deduced the key market drivers and the COVID-19 pandemic impact on the binders excipients industry. The holistic analysis of the drivers will help in deducing end goals and refining marketing strategies to gain a competitive edge.

Key Market Driver

The increasing demand for cellulose-based binders is one of the key drivers fueling the binders excipients market growth. Binder excipients form an inherent part of the pharmaceutical industry. The demand for binder excipients is anticipated to increase rapidly during the forecast period, owing to their use in pharmaceutical drugs. These add volume to low-active-dose tablets and provide mechanical strength to the tablets.  Several companies are expanding their production capacity of cellulose-based binders.

For instance, Asahi Kasei Corp. is one of the major companies in Japan offering tablet binders. In January 2021, the company announced the plan to set up a second plant in Kurashiki city in Japan for the production of Ceolus, a cellulose-based binder. Such an increase in production will drive the market growth during the forecast period.

Significant Market Trend

Demand for new excipients to develop easily consumable drugs is one of the key binders excipients market trends supporting the market growth. The demand for novel excipients, new chemically modified grade excipients, existing excipients with diverse routes of administration, and co-processed excipients is increasing. These excipients enhance the scope for the creation of new formulations and drug delivery systems. The increasing demand for pharmaceutical drugs, such as generic drugs is increasing the demand for pharmaceutical excipients. 

Moreover, to meet the growing demand, pharmaceutical companies are investing in the establishment or expansion of their manufacturing units. In October 2021, BENEO GmbH launched galenIQ 721, a filler binder for pharmaceutical tablets. The water-soluble excipient helps consumers swallow normal tablets easily. Such developments are expected to accelerate the growth of the binders excipients market in the region during the forecast period. 

Major Market Challenge

Loss of patents and patent expiry is one of the factors hindering the binders excipients market growth. The loss of patents and patents getting expired eventually leads to an influx of generic products in the market and large players tend to lose their competitive edge and profit margins. This affects not only the businesses of end-users but also the growth of the market. Allegations associated with the infringement of patents and other intellectual property rights of third parties affect the business of pharmaceutical drug manufacturers. 

For instance, the patent of certain drugs, such as Entresto, Promacta, Rubraca, Mektovi, and Votrient, will expire in 2023. Generic drugs available for off-patent products will affect the sales of these companies. Thus, the patent expiration of pharmaceutical drugs will reduce the consumption of pharmaceutical excipients, including binders, which will hinder the growth of the market during the forecast period.

Market Segmentation

Type Analysis 

The market share growth by the cellulosics segment will be significant during the forecast years. Pharmaceutical formulations employ various excipients, including binders, to ensure the proper manufacturing and administration of oral medicines. Binders, primarily cellulose derivatives such as hydroxypropyl methylcellulose (HPMC), hydroxypropylmethylcellulose acetate (HPMCAS), and microcrystalline cellulose (MCC), play a crucial role in the production of tablets and capsules. HPMC is also utilized as a compression aid and coating agent for tablets, contributing to the growing demand for binders excipients in the pharmaceutical industry. The therapeutic effect of medicinal drugs relies on accurate dosing, which is facilitated by the use of binders.

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The cellulosics segment accounted for USD 534.30 million in 2018. Cellulose derivatives, such as HPMC, offer advantages like convenience, stability, and compatibility with various active pharmaceutical ingredients. In addition, they are used in the production of modified-release tablets, nutraceuticals, and dietary supplements, further expanding their applications. The global binders excipients market is driven by the increasing demand for oral medicines, the rising preference for natural polymers, and the development of innovative therapies. The market is expected to witness significant growth during the forecast period due to the increasing production of generic and branded drugs, the introduction of novel and co-processed excipients, and the estimates generated through rigorous research methodologies and subject-related expert advice. In summary, the global market for binders excipients is expected to grow due to the increasing demand for oral medicines, the rising preference for natural polymers, and the development of innovative therapies.

Region Analysis

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APAC is estimated to contribute 38% to the growth of the global market during the projection period.
Technavio's analysts have provided extensive insight into the market forecasting, detailing the regional trends and drivers influencing the market's trajectory throughout the projection period. China and Japan are the key markets for the market in APAC. Market growth in this region will be faster than the growth of the market in other regions. The increasing health consciousness among consumers will facilitate market growth in APAC over the forecast period. This market research report entails detailed information on the competitive intelligence, marketing gaps, and regional opportunities in store for companies, which will assist in creating efficient business plans.

Key Companies

Companies are implementing various market growth and forecasting strategies by analyzing factors such as strategic alliances, partnerships, mergers and acquisitions, geographical expansion, and product or service launches, to enhance their presence in the market.

Colorcon Inc.- The company offers binder excipient namely Starch 1500.

The report also includes detailed analyses of the competitive landscape of the market and information about 15 market companies, including: 

Asahi Kasei Corp., Ashland Inc., BASF SE, Beneo GmbH, CD Formulation, Colorcon Inc., DFE Pharma GmbH and Co. KG, Dow Chemical Co., DuPont de Nemours Inc., Evonik Industries AG, Fuji Chemical Industries Co. Ltd., Ingredion Inc., JRS PHARMA GmbH and Co. KG, Kerry Group Plc, Merck KGaA, Roquette Freres SA, and Scope Ingredients Pvt. Ltd.

Qualitative and quantitative analysis of companies has been conducted to help clients understand the wider business environment as well as the strengths and weaknesses of key market players. Data is qualitatively analyzed to categorize companies as pure play, category-focused, industry-focused, and diversified; it is quantitatively analyzed to categorize companies as dominant, leading, strong, tentative, and weak.

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Segment Overview

The market research report provides comprehensive data (region wise segment analysis), with forecasts and estimates in "USD Million" for the period 2024 to 2028, as well as historical data from 2018 to 2022 for the following segments

• Type Outlook 
  • Cellulosics
  • Lactose
  • Polyols
  • Povidones
  • others

• Application Outlook
  • Tablets or capsules
  • Solution-based

• Region Outlook 
  • North America
    • The U.S.
    • Canada
  • Europe
    • U.K.
    • Germany
    • France
    • Rest of Europe
  • APAC
    • China
    • India
  • Middle East & Africa
    • Saudi Arabia
    • South Africa
    • Rest of the Middle East & Africa

Market Analyst Overview

The market is pivotal in ensuring the efficacy of pharmaceutical products, particularly in capsule formulations. By regulating the release of active ingredients, these excipients contribute directly to the therapeutic effect of medications. Leveraging natural polymers alongside synthetic counterparts, they offer convenience and enable accurate dosing in various drug delivery systems, including novel drug delivery systems and modified-release tablets. They play a crucial role in formulating nutraceuticals and dietary supplements, providing health benefits to consumers. Through their use in branded drugs and innovative therapies, they ensure stability and consistency in drug formulations, enhancing drug delivery characteristics across liquid formulations, granules, and direct compression methods.

In the market, key factors like the release of active ingredients and their subsequent therapeutic effect are paramount. Excipients such as solvents play a crucial role in formulating pharmaceutical products by ensuring proper dissolution and delivery of active pharmaceutical ingredients (APIs). Components like Polyvinylpyrrolidone (PVP) contribute to the desired release profile and enhance the mechanical properties of dosage forms. Moreover, compatibility between excipients and APIs is vital for maintaining drug stability. Other components like fillers, diluents, disintegrants, lubricants, and coloring agents aid in the formulation process, with substances like lactose, metallic stearate, and talc commonly used in granulation processes.

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What are the Key Data Covered in this Market Research Report?

• CAGR of the market forecast during the forecast period
• Detailed information on factors that will drive the growth of the market  between 2024 and 2028
• Precise estimation of the size of the market and its contribution  in focus to the parent market
• Accurate predictions about upcoming market trends and changes in consumer behavior
• Growth of the market across APAC, North America, Europe, Middle East and Africa, and South America
• Thorough market analysis and report of the market’s competitive landscape and detailed information about companies
• Comprehensive analysis of factors that will challenge the growth of market companies

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